Energy
Contributes to normal energy-yielding metabolism.
Prime Vitality
Have an account? Log in to check out faster.
Active, methylated B vitamins in high-impact doses, the forms your body actually absorbs. Made in Britain.
Backed by 200+ clinical studiesSwipe through what your active B vitamins support.
Contributes to normal energy-yielding metabolism.
Helps reduce tiredness and fatigue.
Supports normal psychological function.
Supports the normal function of the nervous system.
Supports the normal function of the immune system.
Supports the maintenance of normal skin and hair.
Published research on the B vitamins in our formula, which we provide in their active forms.
Backed by 200+ clinical studies
younger memory scores
in a 3-year folate trial
FACIT, double-blind, 818 adults
memoryIn the FACIT trial, 818 adults aged 50 to 70 with raised homocysteine took 800µg of folic acid every day for 3 years and scored on memory tests like people about 4.7 years younger. Our formula provides folate (vitamin B9) too, but as L-5-MTHF (methylfolate), the active form the body can use directly without first converting it. Folate contributes to normal psychological function.
FACIT trial · double-blind, randomised · Durga et al., The Lancet, 2007 · PMID 17240287
mood, over 12 months
in a double-blind vitamin trial
Benton et al., 1995, 129 adults
moodIn a double-blind trial, 129 healthy young adults took a daily supplement of nine vitamins, at ten times the recommended daily amounts, for 12 months. Those on the vitamins reported better mood than those on placebo, most clearly among the women, and the improvement tracked their rising vitamin B2 and B6 status. We include B2 and B6, with folate and B12, in their active forms: R5P, P5P, methylfolate and methylcobalamin. B6, folate and B12 contribute to normal psychological function.
Benton et al. · Neuropsychobiology, 1995 · double-blind, placebo-controlled · PMID 7477807
better absorbed
vs standard thiamine (vitamin B1)
Xie et al., 2014, pharmacokinetic study
energyBenfotiamine is a fat-soluble derivative of thiamine (vitamin B1) that the body takes up more easily than standard thiamine hydrochloride. In a pharmacokinetic study in healthy volunteers, it raised blood (plasma) thiamine to roughly 11 times the level reached from thiamine hydrochloride (a relative bioavailability of 1147%) and roughly doubled the active coenzyme form in red blood cells. That superior absorption is why we chose it.
Xie et al. · pharmacokinetic study, benfotiamine vs thiamine hydrochloride · 2014 · PMID 24399744
mental tiredness, after 33 days
in a high-dose B complex trial
Kennedy et al., 2010, double-blind, 215 men
energyIn a double-blind trial, 215 healthy working men aged 30 to 55 took a high-dose B complex (with vitamin C and minerals) every day for 33 days. Compared with placebo, they rated themselves less mentally tired after demanding mental tasks and reported more vigour. Our formula is a high-dose B complex too, with B2, B3, B5, B6, folate and B12 in their active forms. Those six B vitamins contribute to the reduction of tiredness and fatigue.
Kennedy et al. · Psychopharmacology, 2010 · double-blind, placebo-controlled · PMID 20454891
lower homocysteine
in adults with the common MTHFR gene type
McNulty et al., 2006, MTHFR 677TT
methylationLots of people carry a common variation in the MTHFR gene that slows how their body handles folate. In a double-blind trial, 35 adults with this 677TT gene type took riboflavin (vitamin B2) at 1.6mg a day, or a placebo, for 12 weeks. Homocysteine fell by about 22% across the riboflavin group, and by as much as 40% in those who started with lower riboflavin levels. We include riboflavin as its active R5P form, alongside folate, B6 and B12. Folate, B6 and B12 contribute to normal homocysteine metabolism.
McNulty et al. · Circulation, 2006 · double-blind · MTHFR 677TT adults · PMID 16380544
lower homocysteine
across 25 randomised trials
Homocysteine Lowering Trialists' Collaboration, 2005
methylationA meta-analysis pooling 25 randomised trials (2,596 people) found that folic acid lowered homocysteine by about 23% at a dose of 0.8mg a day. Our formula delivers folate (vitamin B9) as L-5-MTHF (methylfolate), the active form the body uses directly, without the conversion step folic acid needs. Folate contributes to normal homocysteine metabolism.
Homocysteine Lowering Trialists' Collaboration · meta-analysis of 25 randomised trials · American Journal of Clinical Nutrition, 2005 · PMID 16210710
Results from published clinical studies on the active nutrients and forms we use, not claims about the finished product. Food supplements are not a substitute for a varied, balanced diet and a healthy lifestyle.
Real customers, in their own words, on video.
I've been taking Prime Vitality for a couple of weeks, and the noticeable differences are huge.”
Tristan, Croydon
I cannot tell you the difference it's made. I feel like I've had a good sleep, I wake up in the mornings with energy.”
Jacqui, West Yorkshire
They've really refreshed my energy levels.”
Rachel, Lancashire
More customer stories
Nathan, Wales
Callum, Manchester
Helen, Nottinghamshire
Gemma, Derbyshire
Sutha, London
who feel the difference every day.
"Ordered these for my husband and me a few weeks ago and we have both noticed a real difference in our energy. Ordering more soon."
"My partner and I both feel much more energetic after a few weeks. So much better than the store multivitamins. Buying again."
"I did not realise I was low in B12 until I started these. Ten weeks on and I feel so much better, more energy, more focus, up and ready for the day."
"I was tired most of the time. Taking this every morning I am not constantly tired anymore. A massive difference."
"My energy just feels better. I am not as tired through the day and I am getting more done without thinking about it."
"I had been feeling flat all the time. Since taking this my energy has picked up and I feel sharper, more like myself again."
"I have tried loads of supplements and most end up in the cupboard. This is one of the few I have stuck with. I feel more focused and sharper day to day."
"Excellent product. After a few weeks I have a lot more energy in the afternoons, which I really needed. Will buy again."
"Really impressed. I cannot believe how much these have helped me. Thank you to the Prime team for answering my questions."
"Really like these. I feel more awake and focused since I started taking them each morning."
"These have become part of my daily routine and I feel really good for it. So pleased I found a quality B complex made in Britain."
"A month in and I can honestly feel the difference. I have more energy through the day and feel really good taking them."
"Four months in and I feel great taking these every day. I have even got my husband on them too. Really happy with them."
"Good quality B vitamins and the team were really helpful with all of my questions. Thank you."
"I had been struggling with tiredness for a while. A few weeks on these and I have more energy and feel more like myself again."
"I didn't expect much but after a week or so I noticed I wasn't as exhausted by the end of the day. Just feels easier to get through things."
"I've tried a few supplements before and never stuck with them. This is one of the first where I've actually felt a difference, mainly with energy."
"Mornings used to be a struggle but they feel a bit smoother now. Not a huge change, just more consistent which I like."
"I've been taking it for about 3 weeks and feel less foggy at work. I'm getting through tasks quicker without overthinking everything."
"It's been good so far. I do feel a bit more energy and less drained, just wish I'd noticed it a bit sooner."
"Energy feels more level throughout the day. I'm not getting that dip in the afternoon like I used to."
"I bought this after feeling constantly tired and it's helped more than I expected. I just feel a bit more like myself again."
"Didn't expect much but after a couple of weeks I noticed I was a lot less tired after work. Small change but it's made a difference day to day."
"I mainly bought it for energy but I've actually felt a bit more focused as well. Just feel a bit more on it, especially in the mornings."
"It's good, definitely feel a bit more energy and less foggy. Not a massive change but enough that I'll keep taking it."
"I've been using this for about a month and I just feel more balanced. Hard to explain but I'm not as drained by the end of the day."
"I train a lot and normally feel wiped after work, but this has helped keep my energy more consistent. Doesn't feel like a stimulant, which I like."
"I was a bit sceptical but I do feel better on this. Less sluggish in the mornings and I don't rely on coffee as much."
"Honestly didn't expect to notice anything but I actually have. Feel a bit sharper and not as forgetful during the day."
"I've tried cheaper ones before and never noticed a difference. This one feels cleaner somehow, energy is just more even."
"Been taking it for a few weeks now and I'd say I just feel better overall. More energy and a bit more motivation to get things done."
"It's alright. I do feel a bit more energy and slightly less foggy, just not as much as I was hoping for. I'll probably finish the bottle and see how it goes."
"I didn't expect much if I'm honest. But I've been a bit less forgetful at work and just feel a bit sharper overall."
"I've been using it for a couple of months now. It's quite subtle but I feel more balanced, especially with energy. I'm not relying on coffee as much."
"It's decent. I've noticed a bit more energy and focus, just not as much as I hoped. Still better than others I've tried though."
"I bought this after a friend mentioned it. Took a week or so but I do feel less tired in the mornings. Getting up is a bit easier now."
"I train most days and work full time, so I'm usually knackered. This has helped take the edge off that constant tired feeling."
"I've tried cheaper B vitamins and never felt anything. This one feels different, hard to explain but I just feel more switched on."
"Been taking it for about 3 weeks. Energy is more stable and I'm not dipping in the afternoon like before."
"I'm quite sceptical with supplements but this has surprised me. I feel more alert during the day and less drained after work."
"I've been using it just over a month. I'd say the main difference is I don't feel as run down. It's subtle but definitely there."
"I normally hit a wall around 3pm. That's eased off quite a bit since starting this, which has been really helpful with work."
"I've stuck with this longer than anything else I've tried. I just feel a bit more clear headed and less foggy."
"Didn't think I'd notice anything but I actually have. Energy feels smoother and not up and down like before."
"I've been taking it for 6 weeks now. Looking back, I was more tired than I realised. I've definitely got more about me now."
"I like that it doesn't feel like a stimulant. Just gives me a bit more energy to get through the day without feeling wired."
"Mornings are a lot easier now. I used to feel really slow getting going, but that's improved quite a bit."
"I've tried loads of things for energy and this is one of the few I've actually noticed. Nothing crazy, just feel better overall."
See how Prime Vitality compares.


Most B-complex supplements use cheap, synthetic forms your body has to convert first, and often can't. We start with the active, methylated forms, ready to absorb from your very first tablet. Just one a day.
Science-backed, high-impact ingredients.

Built from lived experience. Backed by better ingredients.
It started with a simple question: why do so many supplements promise the world but leave you feeling exactly the same?
After years of trying generic B-complex products and not feeling a difference, I set out to build a formula using the active, methylated forms of B vitamins your body can actually use.
Every batch is made in Britain to high quality standards, vegan, non-GMO, and designed for real life: one tablet, once a day.
Jackson, Founder
Pick your plan and start today.
Shop Now →Get
your first order
Get
your first order, plus honest, science-led notes on getting your B vitamins right.
Here is your welcome code. Use it at checkout for 10% off your first order. We have emailed it to you as well.